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Gatekeepers and progenitor cells in preneoplastic lesions and very early HCC

Various sources

High-grade dysplastic nodules are pre-neoplastic lesions in cirrhotic patients. Different studies indicate that 30% of them degenerate over time. This project will try to determine the primordial molecular changes during this transformation by analyzing a set of high-grade dysplastic nodules and early HCC. Analysis will also include their evaluation as potential niches of cancer stem cells.

Translational research in liver cancer

Liver Cancer Translational Research Laboratory

BCLC-IDIBAPS, Liver Unit, Hospital Clínic · Esther Koplowitz Center, 3rd Floor
Rosselló 153 · 08036 Barcelona · Tel: +34 93 227 9155

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